Inhibikase Says FDA Clears IND For IkT-001Pro To Treat Chronic Myelogenous Leukemia

RTTNews | 1119 दिनों पहले
Inhibikase Says FDA Clears IND For IkT-001Pro To Treat Chronic Myelogenous Leukemia

(RTTNews) - Pharmaceutical company Inhibikase Therapeutics, Inc. (IKT) announced Friday that the U.S. Food and Drug Administration (FDA) has reviewed its Investigational New Drug (IND) application for IkT-001Pro for the treatment of Chronic Myelogenous Leukemia (CML) and issued a Study May Procced (SMP) letter.

IkT-001Pro is a prodrug formulation of imatinib mesylate and has been developed to improve the safety of the first FDA-approved Abelson (Abl) kinase inhibitor, imatinib (marketed as Gleevec).

IkT-001Pro has the potential to be a safer alternative for patients and may improve the number of patients that reach and sustain major and/or complete cytogenetic responses in stable-phase CML.

In preclinical studies, IkT-001Pro was shown to be as much as 3.4 times safer than imatinib in non-human primates, reducing burdensome gastrointestinal side effects that occur following oral administration.

Imatinib delivered as IkT-001Pro was granted Orphan Drug Designation for stable-phase CML in September, 2018.

IkT-001Pro will be evaluated in a single ascending dose bioequivalence study and will enroll approximately 64 male and female healthy volunteers aged 25 to 55 who will receive IkT-001Pro at one of four doses.

For More Such Health News, visit rttnews.com

टैग: IKT
read more
European Economic News Preview: UK Retail Sales & PSNB Data Due

European Economic News Preview: UK Retail Sales & PSNB Data Due

Retail sales and public sector finance from the UK and business confidence from France are the top economic news due on Friday. At 2.00 am ET, the Office for National Statistics publishes UK retail sales and public sector finance figures. Retail sales are forecast to grow 0.4 percent on a monthly basis in August, slower than the 0.6 percent rise in July.
RTTNews | 1घंटे 17 मिनट पहले
European Shares Seen Tad Lower At Open

European Shares Seen Tad Lower At Open

European stocks are seen opening flat to slightly lower on Friday as a busy week for central bank meetings and key economic releases draws to an end.
RTTNews | 1घंटे 31 मिनट पहले
Sensex, Nifty Open Lower After Three Days Of Gains

Sensex, Nifty Open Lower After Three Days Of Gains

Indian shares traded lower on Friday due to profit taking after recent gains supported by GST reforms and encouraging progress in India-U.S. trade discussions.
RTTNews | 2घंटे 26 मिनट पहले
Australian Market Trims Early Gains In Mid-market

Australian Market Trims Early Gains In Mid-market

The Australian stock market is trimming its early gains in mid-market moves on Friday, reversing the losses in the previous two sessions, following the broadly positive cues from Wall Street overnight. The benchmark S&P/ASX 200 is moving up near the 8,800 level, with gains in financial, energy and technology stocks partially offset by a mixed performance in mining stocks.
RTTNews | 3घंटे 45 मिनट पहले
Asian Markets Trade Mixed

Asian Markets Trade Mixed

Asian stock markets are trading mixed on Friday, following the broadly positive cues from Wall Street overnight, as traders continued to digest the US Fed's interest rate cut by a quarter point and its impact on the markets. Fed officials' forecasts suggest two more rate cuts this year but just one next year, although there were significant differences of opinion about the outlook.
RTTNews | 4घंटे 4 मिनट पहले
Sensex, Nifty Eye Cautious Start After Recent Gains

Sensex, Nifty Eye Cautious Start After Recent Gains

Indian shares are seen opening little changed on Friday after recent gains supported by GST reforms and encouraging progress in India-U.S. trade discussions.
RTTNews | 4घंटे 33 मिनट पहले
Thai Shares May Halt Slide On Friday

Thai Shares May Halt Slide On Friday

The Thai stock market has moved lower in consecutive trading days, shedding more than 10 points of 0.8 percent along the way. The Stock Exchange of Thailand now sits just beneath the 1,300-point plateau, although it may find support on Friday.
RTTNews | 5घंटे 6 मिनट पहले