Vertex Pharma To Acquire ViaCyte For $320 Mln In Cash

Vertex Advances Inaxaplin Into Phase 2/3 Trial To Treat APOL1-Mediated Kidney Disease

Vertex Pharmaceuticals Inc. (VRTX) announced Monday that inaxaplin (VX-147) has advanced into the Phase 3 portion of the global Phase 2/3 pivotal clinical trial in APOL1-mediated kidney disease (AMKD), where a 45 mg once daily oral dose will be compared to placebo, on top of standard of care.

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Vertex Receives CHMP Positive Opinion For The First CRISPR/Cas9 Gene-Edited Therapy CASGEVY

Vertex Pharmaceuticals Inc. (VRTX) announced Friday that the European Medicines Agency's (EMA's) Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion for the conditional approval of CASGEVY (exagamglogene autotemcel [exa-cel]), a CRISPR/Cas9 gene-edited therapy, for the treatment of severe sickle cell disease (SCD) and transfusion-dependent beta thalassemia (TDT).

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Vertex Pharma Inks Licensing Agreement To Use CRISPR Therapeutics' Gene Editing Technology

Biotechnology company Vertex Pharmaceuticals, Inc. (VRTX) and gene editing company CRISPR Therapeutics, Inc. (CRSP) announced Monday that they have entered into a new non-exclusive licensing agreement for the use of CRISPR Therapeutics' gene editing technology, known as CRISPR/Cas9, to accelerate the development of Vertex's hypoimmune cell therapies for type 1 diabetes (T1D).

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Vertex Pharma Says FDA Lifts Clinical Hold On Phase 1/2 Trial Of VX-880 To Treat Type 1 Diabetes

Vertex Pharmaceuticals Inc. (VRTX) announced Tuesday that the U.S. Food and Drug Administration (FDA) has lifted the clinical hold placed on the Phase 1/2 clinical trial of VX-880, an investigational stem cell-derived, fully differentiated pancreatic islet cell replacement therapy for people with type 1 diabetes (T1D) with impaired hypoglycemic awareness and severe hypoglycemia.

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Japan Trade Data Due On Wednesday

Japan will on Wednesday release October figures for imports, exports and trade balance, highlighting a busy day for Asia-Pacific economic activity.

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Swiss Stocks Close Notably Lower On Weak Global Cues

The Switzerland market ended weak on Tuesday, in line with markets across Europe and elsewhere, as worries fears of Artificial Intelligence bubble, uncertainty about interest rates, and a lack of positive economic data rendered the mood bearish.

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European Markets Drop To Multi-week Lows On Growth Worries, Rate Uncertainty

European stocks closed weak on Tuesday, and several markets in the region dropped to multi-week lows, as worries about lofty valuations of Artificial Intelligence-related stocks, and uncertainty about interest rate moves by global central banks, including the Federal Reserve, rendered the mood cautious and forced investors to trim down long positions.

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TSX Down Nearly 0.5% Despite Coming Off Early Lows

The Canadian market continues to languish in negative territory a little past noon on Tuesday, despite recovering from early lows. Worries about lofty valuations of AI-related stocks, and uncertainty about the Federal Reserve's upcoming interest rate moves weigh on sentiment, prompting investors to trim down positions.

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EURUSD	1.15807	GBPUSD	1.31472	AUDUSD	0.6511
USDJPY	155.52	USDCAD	1.39853	USDCHF	0.79997