89bio Reports Positive Topline Data From Extended Phase 2b ENLIVEN Trial Of Pegozafermin

RTTNews | 574 gün önce
89bio Reports Positive Topline Data From Extended Phase 2b ENLIVEN Trial Of Pegozafermin

(RTTNews) - Biopharmaceutical company 89bio, Inc. (ETNB) announced Monday positive topline data from the blinded extension phase of its Phase 2b ENLIVEN trial evaluating treatment with pegozafermin in patients with nonalcoholic steatohepatitis (NASH).

At week 48, both the 30mg weekly (QW) and 44mg every-two-week (Q2W) dosing schedules of pegozafermin demonstrated statistically significant improvements across key markers of liver health.

The benefits observed at week 48 were consistent with the results observed at week 24, indicating sustained benefits over time.

Patients in ENLIVEN continued in a blinded extension phase for an additional 24 weeks (Extension Phase) past the primary endpoint at week 24 (Main Study), for a total treatment period of 48 weeks.

Etiketler: ETNB
read more
DAX Dips As Middle East Crisis Deepens

DAX Dips As Middle East Crisis Deepens

Amidst weak sentiment triggered by the U.S. attacks on Iran and fears of Iran's response thereto, the DAX is trading in mildly negative territory.
RTTNews | 38 dakika önce
Yen Slides Against Majors

Yen Slides Against Majors

The Japanese yen weakened against other major currencies in the European session on Monday.
RTTNews | 1s 25 dakika önce
Sensex, Nifty End Off Day's Lows

Sensex, Nifty End Off Day's Lows

Indian shares fell on Monday, but ended off their day's lows as markets apparently took the U.S. strikes against nuclear targets in Iran in their stride and waited to see how Iran reacts and what happens to Tehran's nuclear program.
RTTNews | 1s 26 dakika önce
German Private Sector Returns To Growth

German Private Sector Returns To Growth

Germany's private sector returned to growth in June, led by the manufacturing sector, flash data from S&P Global revealed on Monday.The HCOB composite output index stood at 50.4 in June, rebounding from a five-month low of 48.5 in May. A reading above the neutral 50.0 level signals expansion in the sector. Growth in manufacturing output was partly offset by a slower reduction in services activty
RTTNews | 1s 44 dakika önce
Antipodean Currencies Fall Amid Risk-Off Mood

Antipodean Currencies Fall Amid Risk-Off Mood

The antipodean currencies such as the Australia and the New Zealand dollars weakened against other major currencies in the Asian session on Monday due to increased risk-off mood by the investors, amid escalation in the middle east conflict after the U.S. joined Israel in the weeks-long war with Iran, with U.S. carrying out a "successful" airstrike on three nuclear sites in Iran over the weekend. This has heightened fears of a broader regional conflict.
RTTNews | 1s 53 dakika önce
French Private Sector Downturn Deepens

French Private Sector Downturn Deepens

France's private sector output declined further in June as both manufacturing and services activity entered the contraction territory, flash survey results from S&P Global showed on Monday. The HCOB flash composite output index declined to 48.5 in June from 49.3 in the previous month. A reading below 50.0 indicates contraction.
RTTNews | 2s 10 dakika önce