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89bio Reports Positive Topline Data From Extended Phase 2b ENLIVEN Trial Of Pegozafermin
(RTTNews) - Biopharmaceutical company 89bio, Inc. (ETNB) announced Monday positive topline data from the blinded extension phase of its Phase 2b ENLIVEN trial evaluating treatment with pegozafermin in patients with nonalcoholic steatohepatitis (NASH).
At week 48, both the 30mg weekly (QW) and 44mg every-two-week (Q2W) dosing schedules of pegozafermin demonstrated statistically significant improvements across key markers of liver health.
The benefits observed at week 48 were consistent with the results observed at week 24, indicating sustained benefits over time.
Patients in ENLIVEN continued in a blinded extension phase for an additional 24 weeks (Extension Phase) past the primary endpoint at week 24 (Main Study), for a total treatment period of 48 weeks.
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Australian Market Trims Early Losses In Mid-market
The Australian stock market is trimming is early losses in mid-market trading on Tuesday, reversing the slight gains in the previous session, following the mixed cues from Wall Street overnight. The benchmark S&P/ASX 200 is staying well below the 8,700 level, with weakness in financial and technology stocks partially offset by some gains in energy stocks.
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5 นาทีที่ผ่านมา
Asian Markets Trade Mostly Lower
Asian stock markets are trading mostly lower on Tuesday, following the mixed cues from Wall Street overnight, as traders remain cautious ahead of the U.S. interest rate decision later in the week and as they await the outcome of the U.S.-China trade talks. Meanwhile, several European leaders voiced concerns over the EU-U.S. trade deal, calling it 'lopsided' and 'unsustainable'.
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12 นาทีที่ผ่านมา
Sensex, Nifty Set To Extend Losses On Trade Deal Uncertainty
Indian shares are seen opening lower on Tuesday after several European leaders voiced concerns over the EU-U.S. trade deal, calling it 'lopsided' and 'unsustainable'.
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48 นาทีที่ผ่านมา
Thai Shares Likely To Remain Rangebound
Ahead of Monday's holiday for King Maha's birthday, the Thai stock market had alternated between positive and negative finishes through the last four trading days since the end of the three-day winning streak in which it had spiked more than 50 points or 4.1 percent. The Stock Exchange of Thailand now sits just above the 1,215-point plateau and it's expected to remain in that neighborhood again on Tuesday.
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1 ชม. 28 นาทีที่ผ่านมา
Japanese Market Significantly Lower
The Japanese stock market is trading significantly lower on Tuesday, extending the losses in the previous two sessions, following the mixed cues from Wall Street overnight, with the Nikkei 225 falling well above the 39,700 level, with weakness across all sectors led by automakers, exporters and financial stocks.
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1 ชม. 58 นาทีที่ผ่านมา
Win Streak May End For Indonesia Stock Market
The Indonesia stock market has moved higher in four straight sessions, advancing more than 260 points or 2.8 percent along the way. The Jakarta Composite Index now sits just above the 7,610-point plateau although investors are likely to cash in on Tuesday.
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1 ชม. 58 นาทีที่ผ่านมา
Hong Kong Shares Tipped To Open Under Pressure
The Hong Kong stock market rebounded on Monday, one session after ending the five-day winning streak in which it had rallied almost 1,300 points or 5.1 percent. The Hang Seng Index now sits just above the 25,560-point plateau although it may hand back those gains on Tuesday.
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2 ชม. 13 นาทีที่ผ่านมา
China Shares May Head South Again On Tuesday
The China stock market moved back to the upside again on Monday, one session after halting the six-day winning streak in which it had advanced more than 100 points or 2.8 percent. The Shanghai Composite Index now sits just beneath the 3,600-point plateau although it may spin its wheels again on Tuesday.
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2 ชม. 28 นาทีที่ผ่านมา
