Genmab Submits NDA For Epcoritamab In Japan For Relapsed/Refractory Large B-Cell Lymphoma

RTTNews | Před 957 dny
Genmab Submits NDA For Epcoritamab In Japan For Relapsed/Refractory Large B-Cell Lymphoma

(RTTNews) - Genmab A/S (GMAB) announced Wednesday that the company has submitted a Japan new drug application (JNDA) to the Ministry of Health, Labor and Welfare (MHLW) of Japan for subcutaneous epcoritamab (DuoBody-CD3xCD20)

Epcoritamab is an investigational bispecific antibody, for the treatment of patients with relapsed/refractory (R/R) large B-cell lymphoma (LBCL) after two or more lines of systemic therapy.

The JNDA submission is supported by the EPCORE NHL-3, open-label, multi-center, phase 2 trial (GCT3013-04) evaluating the safety and preliminary efficacy of epcoritamab in adult patients in Japan with relapsed, progressive or refractory CD20+ mature B-cell non-Hodgkin lymphoma (B-NHL), as well as results from the global EPCORE NHL-1 open-label, multi-center, phase 2 trial (GCT3013-01) evaluating epcoritamab in the same patient population.

Epcoritamab is being co-developed by Genmab and AbbVie as part of the companies' oncology collaboration. The companies will share commercial responsibilities in the U.S. and Japan, with AbbVie responsible for further global commercialization.

For More Such Health News, visit rttnews.com

read more
Sensex, Nifty Open Lower After Trump's Fresh Tariff Threat

Sensex, Nifty Open Lower After Trump's Fresh Tariff Threat

Indian shares opened on a sluggish note Tuesday after U.S. President Donald Trump threatened to "substantially" raise tariffs on goods imported from India, accusing that the country profited from Russia's war in Ukraine by purchasing large quantities of Russian oil and reselling it on the global market.
RTTNews | Před 33 minutami
Australian Market Extends Early Gains In Mid-market

Australian Market Extends Early Gains In Mid-market

The Australian stock market is extending its early gains in mid-market trading on Tuesday, adding to the gains in the previous session, following the broadly positive cues from Wall Street overnight. The benchmark S&P/ASX 200 is moving above the 8,750 level, with gains across all sectors led by mining, energy and technology stocks.
RTTNews | Před 1 h 38 min
Asian Markets Track Wall Street Higher

Asian Markets Track Wall Street Higher

Asian stock markets are trading mostly higher on Tuesday, following the broadly positive cues from Wall Street overnight, amid optimism the weak monthly US jobs data will lead the US Fed to lower interest rates next month. Traders also picked up stocks at a bargain following the recent downturn in the markets. Asian markets closed mixed on Monday.
RTTNews | Před 2 h 3 min
Sensex, Nifty Set To Open Lower As Trump Again Threatens India With Harsh Tariffs

Sensex, Nifty Set To Open Lower As Trump Again Threatens India With Harsh Tariffs

Indian shares may open on a weak note Tuesday after U.S. President Donald Trump threatened to "substantially" raise tariffs on goods imported from India, accusing that the country profited from Russia's war in Ukraine by purchasing large quantities of Russian oil and reselling it on the global market.
RTTNews | Před 2 h 36 min
Additional Support Anticipated For Thai Stock Market

Additional Support Anticipated For Thai Stock Market

The Thai stock market on Monday ended the two-day slide in which it had fallen more than 25 points or 2 percent. The Stock Exchange of Thailand now sits just above the 1,230-point plateau and it's expected to open to the upside again on Tuesday.
RTTNews | Před 3 h 8 min
Japanese Market Modestly Higher

Japanese Market Modestly Higher

The Japanese stock market is trading modestly higher on Tuesday, reversing the losses in the previous two sessions, following the broadly positive cues from Wall Street overnight, with the Nikkei 225 moving well above the 40,400 level, with small gains across most sectors led by exporters, automakers and financial stocks.
RTTNews | Před 3 h 31 min
Rebound Called For Indonesia Stock Market

Rebound Called For Indonesia Stock Market

The Indonesia stock market headed south again on Monday, one session after snapping the two-day slide in which it had dropped almost 140 points or 1.9 percent. The Jakarta Composite Index now sits just shy of the 7,465-point plateau although it's likely to see renewed support on Tuesday.
RTTNews | Před 3 h 38 min
Australian Market Significantly Higher

Australian Market Significantly Higher

The Australian stock market is trading significantly higher on Tuesday, extending the gains in the previous session, following the broadly positive cues from Wall Street overnight. The benchmark S&P/ASX 200 is moving above the 8,700 level, with gains across all sectors led by mining and technology stocks.
RTTNews | Před 3 h 51 min