HilleVax Reports Positive Immunogenicity Results For Phase 2b Trial For HIL-214

RTTNews | 1065天前
HilleVax Reports Positive Immunogenicity Results For Phase 2b Trial For HIL-214

(RTTNews) - Biopharmaceutical company HilleVax, Inc. (HLVX) reported Monday positive results from a prespecified immunogenicity analysis of the 203 subjects enrolled in the run-in cohort of NEST-IN1 (Norovirus Efficacy and Safety Trial for INfants), the company's ongoing Phase 2b trial for HIL-214, its investigational virus-like particle (VLP) based vaccine candidate for the prevention of moderate-to-severe norovirus-related acute gastroenteritis (AGE) in infants.

These results follow the previously announced positive recommendation from an independent safety data monitoring committee based on this same cohort.

NEST-IN1 is a Phase 2b, randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy, safety, and immunogenicity of HIL-214 in infants of approximately 5 months of age at time of initial vaccination at sites in the United States and Latin America.

The study is planned to enroll 3,000 subjects who will be randomized 1:1 to receive a two-dose regimen of either HIL-214 or placebo.

The company said the full NEST-IN1 topline safety and efficacy data remains on-track for the second half of 2023.

For More Such Health News, visit rttnews.com

read more
BoJ Minutes: Japan Economy Recovering But Faces Downside Risks

BoJ Minutes: Japan Economy Recovering But Faces Downside Risks

Members of the Bank of Japan's Monetary Policy Meeting agreed that the country was continuing to see economic recovery, although some downside risks remain, minutes from the central bank's monetary policy meeting on September 17-18 revealed on Wednesday.
RTTNews | 1小時10分鐘前
Singapore Bourse May Give Up Support At 4,400 Points

Singapore Bourse May Give Up Support At 4,400 Points

The Singapore stock market turned lower again on Tuesday, one day after ending the three-day slide in which it had slipped more than 20 points or 0.5 percent. The Straits Times Index now sits just above the 4,420-point plateau and it's likely to open under pressure again on Wednesday.
RTTNews | 1小時11分鐘前
Rally May Stall On Wednesday For Malaysia Shares

Rally May Stall On Wednesday For Malaysia Shares

The Malaysia stock market has finished higher in two straight sessions, collecting almost 15 points or 0.9 percent along the way. The Kuala Lumpur Composite Index now sits just above the 1,620-point plateau although it's likely to run out of steam on Wednesday.
RTTNews | 1小時41分鐘前
Japan Shares Expected To Open Under Pressure

Japan Shares Expected To Open Under Pressure

The Japan stock market on Tuesday wrote a finish to the three-day winning streak in which is had surged almost 2,200 points or 4 percent. The Nikkei 225 now rests just beneath the 51,500-point plateau and it may extend its losses on Wednesday.
RTTNews | 1小時56分鐘前
Continued Consolidation Called For KOSPI

Continued Consolidation Called For KOSPI

The South Korea stock market on Tuesday ended the four-day winning streak in which it had surged almost 215 points or 5.3 percent to a fresh record closing high. The KOSPI sits just above the 4,120-point plateau and it may take further damage on Wednesday.
RTTNews | 2小時11分鐘前
BoJ Minutes On Tap For Wednesday

BoJ Minutes On Tap For Wednesday

The Bank of Japan will on Wednesday release the minutes from its September 18 monetary policy meeting, highlighting a busy day for Asia-Pacific economic activity.
RTTNews | 2小時41分鐘前