Hoth Therapeutics Says FDA Accepts IND Application For HT-001 For Treatment Of Cancer Disorders

RTTNews | hace 860
Hoth Therapeutics Says FDA Accepts IND Application For HT-001 For Treatment Of Cancer Disorders

(RTTNews) - Biopharmaceutical company Hoth Therapeutics, Inc. (HOTH) announced Thursday that the U.S. Food and Drug Administration (FDA) has accepted an Investigational New Drug (IND) application for the company's HT-001 therapeutic for the treatment for rash and skin disorders associated with epidermal growth factor receptor (EGFR) inhibitor therapy.

EGFR inhibitors are critical therapeutic agents for the treatment of non-small cell lung cancer (NSCLC), pancreatic cancer, colorectal cancer, squamous-cell carcinoma of the head and neck, and breast cancer.

The company said this trial brings us one step closer to a new treatment option for underserved cancer patients as there is no specific treatment currently approved for the treatment of skin toxicities associated with EGFRi therapies.

The company added it will advance HT-001 into the clinical phase as it is a key treatment in the onco-dermatology space and anticipates beginning the Phase 2a trial in the first quarter of 2023.

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Hoth Therapeutics' Pre-IND Submission For HT-KIT For Advance Systemic Mastocytosis Accepted By FDA

Hoth Therapeutics' Pre-IND Submission For HT-KIT For Advance Systemic Mastocytosis Accepted By FDA

Biopharmaceutical company Hoth Therapeutics, Inc. (HOTH) announced Monday it has submitted a request for a Pre-Investigational New Drug (IND) meeting to the U.S. Food and Drug Administration (FDA) to discuss the proposed drug development program for HT-KIT, a new molecular entity, for the treatment of advance systemic mastocytosis (AdvSM), a rare aggressive form of cancer.
RTTNews | hace 604
Swiss Market Ends Nearly 1% Down

Swiss Market Ends Nearly 1% Down

Swiss stocks opened on a weak note on Wednesday and languished in negative territory right through the day's session as investors stayed cautious ahead of the Federal Reserve and the Bank of England's monetary policy announcements, due later in the day, and on Thursday, respectively.
RTTNews | hace 37 minutos
Major European Markets Close On Weak Note After Cautious Session

Major European Markets Close On Weak Note After Cautious Session

The major European markets closed weak on Wednesday as investors reacted to earnings announcements, and awaited the monetary policy announcement from the Federal Reserve later in the day. The Bank of England's policy announcement is due on Thursday. Upbeat economic data from Germany, and optimism surrounding upcoming U.S.-China trade talks helped limit markets' downside.
RTTNews | hace 52 minutos
Canadian Stocks Up Firmly In Positive Territory

Canadian Stocks Up Firmly In Positive Territory

The Canadian market is up firmly in positive territory a little past noon on Wednesday, lifted by gains in utilities, technology, consumer and financials sectors. The market undertone is positive amid slightly easing tensions about tariffs ahead of U.S.-China meeting this week, and expectations that the Federal Reserve will hold interest rates unchanged.
RTTNews | hace 1h 36min
German Factory Orders Rebound Ahead Of U.S. Tariffs

German Factory Orders Rebound Ahead Of U.S. Tariffs

Germany's factory orders grew more than expected in March as U.S. manufacturers front-loaded their orders to avoid higher tariffs, official data revealed Wednesday. Factory orders advanced 3.6 percent month-on-month in March after remaining flat in February, Destatis reported. Orders are forecast to grow 1.4 percent.
RTTNews | hace 4h 24min