Hoth Therapeutics Says FDA Accepts IND Application For HT-001 For Treatment Of Cancer Disorders

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Hoth Therapeutics Says FDA Accepts IND Application For HT-001 For Treatment Of Cancer Disorders

(RTTNews) - Biopharmaceutical company Hoth Therapeutics, Inc. (HOTH) announced Thursday that the U.S. Food and Drug Administration (FDA) has accepted an Investigational New Drug (IND) application for the company's HT-001 therapeutic for the treatment for rash and skin disorders associated with epidermal growth factor receptor (EGFR) inhibitor therapy.

EGFR inhibitors are critical therapeutic agents for the treatment of non-small cell lung cancer (NSCLC), pancreatic cancer, colorectal cancer, squamous-cell carcinoma of the head and neck, and breast cancer.

The company said this trial brings us one step closer to a new treatment option for underserved cancer patients as there is no specific treatment currently approved for the treatment of skin toxicities associated with EGFRi therapies.

The company added it will advance HT-001 into the clinical phase as it is a key treatment in the onco-dermatology space and anticipates beginning the Phase 2a trial in the first quarter of 2023.

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Hoth Therapeutics' Pre-IND Submission For HT-KIT For Advance Systemic Mastocytosis Accepted By FDA

Hoth Therapeutics' Pre-IND Submission For HT-KIT For Advance Systemic Mastocytosis Accepted By FDA

Biopharmaceutical company Hoth Therapeutics, Inc. (HOTH) announced Monday it has submitted a request for a Pre-Investigational New Drug (IND) meeting to the U.S. Food and Drug Administration (FDA) to discuss the proposed drug development program for HT-KIT, a new molecular entity, for the treatment of advance systemic mastocytosis (AdvSM), a rare aggressive form of cancer.
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Bay Street May Open On Positive Note Again

Bay Street May Open On Positive Note Again

Canadian stocks may open higher on Wednesday amid optimism about an end to the U.S. government shutdown. Firm European stocks and expectations of an interest rate cut by the Federal Reserve next month may also help underpin sentiment.
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FTSE 100 Pares Early Gains; SSE Soars 12%

FTSE 100 Pares Early Gains; SSE Soars 12%

After opening marginally higher and moving up a bit subsequently, the U.K. market's FTSE 100 slipped into negative territory on Wednesday, with investors looking for direction and largely refraining from making significant moves.
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CAC 40 Extends Gains To 3rd Straight Day, Rises Over 1%

CAC 40 Extends Gains To 3rd Straight Day, Rises Over 1%

French stocks are up in positive territory on Wednesday, extending gains to a third straight session, led by gains in financial and luxury sectors. Expectations of an interest rate cut by the Federal Reserve next month, and hopes that the government shutdown in the U.S. will likely end this week help underpin sentiment.
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DAX Climbs To 4-week High On Inflation Data, Earnings

DAX Climbs To 4-week High On Inflation Data, Earnings

Germany's DAX climbed to a four-week high on Wednesday with investors continuing to pick up stocks amid hopes the US government shutdown will come to an end soon, and expectations of an interest rate cut by the Federal Reserve in December.
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