Hoth Therapeutics Says FDA Accepts IND Application For HT-001 For Treatment Of Cancer Disorders

RTTNews | 859 hari yang lalu
Hoth Therapeutics Says FDA Accepts IND Application For HT-001 For Treatment Of Cancer Disorders

(RTTNews) - Biopharmaceutical company Hoth Therapeutics, Inc. (HOTH) announced Thursday that the U.S. Food and Drug Administration (FDA) has accepted an Investigational New Drug (IND) application for the company's HT-001 therapeutic for the treatment for rash and skin disorders associated with epidermal growth factor receptor (EGFR) inhibitor therapy.

EGFR inhibitors are critical therapeutic agents for the treatment of non-small cell lung cancer (NSCLC), pancreatic cancer, colorectal cancer, squamous-cell carcinoma of the head and neck, and breast cancer.

The company said this trial brings us one step closer to a new treatment option for underserved cancer patients as there is no specific treatment currently approved for the treatment of skin toxicities associated with EGFRi therapies.

The company added it will advance HT-001 into the clinical phase as it is a key treatment in the onco-dermatology space and anticipates beginning the Phase 2a trial in the first quarter of 2023.

read more
Hoth Therapeutics' Pre-IND Submission For HT-KIT For Advance Systemic Mastocytosis Accepted By FDA

Hoth Therapeutics' Pre-IND Submission For HT-KIT For Advance Systemic Mastocytosis Accepted By FDA

Biopharmaceutical company Hoth Therapeutics, Inc. (HOTH) announced Monday it has submitted a request for a Pre-Investigational New Drug (IND) meeting to the U.S. Food and Drug Administration (FDA) to discuss the proposed drug development program for HT-KIT, a new molecular entity, for the treatment of advance systemic mastocytosis (AdvSM), a rare aggressive form of cancer.
RTTNews | 603 hari yang lalu
U.S. Trade Deficit Spikes To Record High In March As Import Surge

U.S. Trade Deficit Spikes To Record High In March As Import Surge

The U.S. trade deficit spiked by much more than expected in the month of March, according to a report released by the Commerce Department on Tuesday. The report said the trade deficit soared to a record high $140.5 billion in March from a revised $123.2 billion in February.
RTTNews | 7 minit yang lalu
Eurozone Private Sector Growth Eases On Weaker Demand

Eurozone Private Sector Growth Eases On Weaker Demand

Euro area private sector growth weakened in April as soft demand conditions limited the speed of expansion and weighed on sentiment, final results of the purchasing managers' survey by S&P Global showed on Tuesday. The HCOB final composite output index fell to 50.4 in April from 50.9 in March, but the reading suggested growth for the fourth straight month.
RTTNews | 1j 10min yang lalu
Bay Street Likely To Open On Mixed Note

Bay Street Likely To Open On Mixed Note

Canadian shares may be weighed down on Tuesday by U.S. President Donald Trump's announcement on Monday that he is likely to announce pharmaceutical tariffs soon. The Federal Reserve's monetary policy announcement, due on Wednesday, is also in focus. However, higher crude oil and metal prices could trigger some buying in energy and materials space.
RTTNews | 1j 46min yang lalu
Philips Cuts FY25 Margin View On Tariffs, Despite Higher Q1 Income, Orders; Stock Down

Philips Cuts FY25 Margin View On Tariffs, Despite Higher Q1 Income, Orders; Stock Down

Shares of Royal Philips N.V. were losing around 3 percent in the mid-day trading in Amsterdam, as well as around 5 percent in pre-market activity on the NYSE, after the Dutch consumer electronics giant on Tuesday trimmed its margin forecast for fiscal 2025 to reflect the estimated net tariff impact of 250 million euros to 300 million euros. Further, the firm maintained annual sales view,...
RTTNews | 2j 50min yang lalu