BioVie Announces Positive Topline Results From Phase 2 Trial Of NE3107 To Treat Alzheimer's Disease

RTTNews | 1064 days ago
Stocktwits
BioVie Announces Positive Topline Results From Phase 2 Trial Of NE3107 To Treat Alzheimer's Disease

(RTTNews) - Clinical-stage company BioVie Inc. (BIVI) announced Wednesday topline results from an investigator-Sponsored Phase 2 clinical trial of NE3107 for the treatment of Alzheimer's Disease (AD).

AD research has largely focused on Amyloid Beta (Ab) and phospho-tau (p-tau) for decades and has resulted in a large number of trials targeting these mechanisms.

NE3107 is the only molecule in this group that is pursuing a two-pronged approach targeting both neuroinflammation and insulin resistance.

The trial measured changes in cognition through verbal and visual test procedures, changes in biomarkers of Alzheimer's disease and inflammation that can be measured in cerebral spinal fluid (CSF) and serum samples, and with functional magnetic resonance imaging techniques in patients before and after treatment with 20 mg of NE3107 twice daily for 3 months.

Initial results showed that the measurements for most patients improved with NE3107 treatment, although mild cognitive impairment (MCI)/mild AD patients showed greater change.

A large proportion of MCI/mild AD patients in the trial showed improvements as evidenced by an increase of the GRoC scale after treatment with NE3107 compared to baseline.

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Tags: BIVI
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Canadian Stocks Surge Higher Again; TSX Scales New Record High

Canadian Stocks Surge Higher Again; TSX Scales New Record High

Canadian stocks are up firmly in positive territory on Wednesday, and the benchmark S&P/TSX Composite Index stays high up after hitting a fresh record. Rising optimism about a rate cut by the Federal Reserve in September, firm oil prices and some upbeat corporate earnings announcements are contributing to the positive mood in the market.
RTTNews | 1h 2min ago
India Holds Key Interest Rates Steady As Trade Tensions Escalate

India Holds Key Interest Rates Steady As Trade Tensions Escalate

The Reserve Bank of India left its key interest rates unchanged on Wednesday after an aggressive cut in June as the economy faces another threat from the US due to its Russian oil imports. The RBI Monetary Policy Committee, led by Governor Sanjay Malhotra, unanimously decided to hold the policy repo rate at 5.50 percent. The bank had reduced the rate by 50 basis points in June.
RTTNews | 3h 34min ago
Bay Street Looks Set To Extend Upmove

Bay Street Looks Set To Extend Upmove

Canadian shares look headed for a positive start on Wednesday, riding on some impressive corporate earnings updates, and higher oil prices. The focus will also be on the developments on the trade front.
RTTNews | 5h 2min ago
Eurozone Retail Sales Recover In June

Eurozone Retail Sales Recover In June

Euro area retail sales rebounded in June suggesting that household spending likely supported economic growth in the second quarter, official data revealed on Wednesday. Retail sales grew 0.3 percent on a monthly basis in June, offsetting May's 0.3 percent decline, Eurostat said. However, this was marginally weaker than economists' forecast for a 0.4 percent increase.
RTTNews | 5h 12min ago
Euro Rises As European Shares Traded Higher

Euro Rises As European Shares Traded Higher

The euro strengthened against other major currencies in the European session on Wednesday, as European shares traded higher despite weak factory orders data from Germany and fresh tariff threats from U.S. President Donald Trump on pharma and chips. Some upbeat earnings announcements and expectations of a Fed interest rate cut next month appear to be aiding sentiment.
RTTNews | 5h 45min ago
Disney Lifts FY25 EPS View After Q3 Profit Beats Market; ESPN In Deal With WWE, NFL

Disney Lifts FY25 EPS View After Q3 Profit Beats Market; ESPN In Deal With WWE, NFL

Media and entertainment major Walt Disney Co. (DIS) on Wednesday raised fiscal 2025 outlook for earnings.above the Street after reporting significantly higher profit in its third quarter, above market estimates. Meanwhile, revenues missed the market view, despite reporting a growth. Separately, Disney announced that its unit ESPN has signed a landmark rights agreement with WWE.
RTTNews | 6h 2min ago
Dynatrace Boosts FY26 Outlook - Update

Dynatrace Boosts FY26 Outlook - Update

While reporting financial results for the first quarter on Wednesday, software intelligence provider Dynatrace, Inc. (DT) provided its adjusted earnings and revenue guidance for the second quarter and raised its outlook for the full-year 2026.
RTTNews | 6h 8min ago
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