Endo Int'l Reports Top-line Results From Phase 2 Study Of CCH For Adhesive Capsulitis Of Shoulder

RTTNews | 1072 days ago
Endo Int'l Reports Top-line Results From Phase 2 Study Of CCH For Adhesive Capsulitis Of Shoulder

(RTTNews) - Pharmaceutical company Endo International plc (ENDP) announced Friday top-line results from its Phase 2 study of Collagenase Clostridium Histolyticum (CCH) in participants with adhesive capsulitis (AC) of the shoulder, commonly known as "frozen shoulder."

The Phase 2 study participants receiving up to three doses of CCH showed some improvement in the change from baseline in the adapted American Shoulder and Elbow Surgeons (ASES) Standardized Shoulder Form composite score for the affected shoulder at the Day 95 visit.

The difference compared to those study participants receiving placebo was not statistically significant.

The safety profile of CCH in the Phase 2 study was consistent with the known safety profile from other studies.

The Phase 2 trial enrolled 198 participants with unilateral idiopathic AC of the shoulder with restricted range of motion (ROM) and function in the affected shoulder. Participants were randomized 1:1 to receive CCH or placebo administered by ultrasound-guided injection.

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Endo Intl's Par Pharma Recalls Treprostinil Injection For Silicone Particulates

Endo Intl's Par Pharma Recalls Treprostinil Injection For Silicone Particulates

Dublin, Ireland -based Endo International plc announced that its operating company Par Pharmaceutical, Inc. is recalling one lot of Treprostinil Injection 20mg/20mL (1mg/mL) to the consumer level. The recall, being conducted along with the U.S. Food and Drug Administration, is due to the potential for the presence of silicone particulates in the product solution.
RTTNews | 451 days ago
Endo International Says Health Canada Approves XCOPRI To Treat Epilepsy

Endo International Says Health Canada Approves XCOPRI To Treat Epilepsy

Specialty pharmaceutical company Endo International plc (ENDPQ.PK) announced Thursday that its operating company Paladin Labs, Inc. (PLB.TO) has received Health Canada's approval of XCOPRI (cenobamate tablets) for adjunctive therapy in the management of partial-onset seizures in adults with epilepsy who are not satisfactorily controlled with conventional therapy.
RTTNews | 709 days ago
U.S. Dollar Higher After Strong Jobs Data

U.S. Dollar Higher After Strong Jobs Data

The U.S. dollar firmed against its major counterparts in the New York session on Friday, following the release of better-than-expected nonfarm payrolls report for May.
RTTNews | 22h 4min ago
Swiss Market Ends Modestly Higher

Swiss Market Ends Modestly Higher

After a flat start and a subsequent modest upmove, the Switzerland market turned subdued and fell into negative territory by noon on Friday, but recovered gradually to finally end the day's session on a positive note.
RTTNews | 23h 37min ago
European Markets Close Higher

European Markets Close Higher

The major European markets closed slightly higher on Friday, supported by data showing stronger-than-expected jobs growth in the U.S., and an upward revision in eurozone first-quarter GDP. Weak industrial production data from Germany and France, and persisting concerns about U.S. tariffs limited markets' upside.
RTTNews | 1 day ago
CPSC Recalls: 3.8 Mln Dumbbells, 1.7 Mln Air Conditioners, Golf Cars, CO Detectors, Casters, E-Bikes

CPSC Recalls: 3.8 Mln Dumbbells, 1.7 Mln Air Conditioners, Golf Cars, CO Detectors, Casters, E-Bikes

The U.S. Consumer Product safety Commission or CPSC has announced various recalls including around 3.8 million units of dumbbells by Johnson Health Tech Trading, 1.7 million air conditioners by Midea America Corp., around 352 thousand units of Yamaha golf cars including previously recalled ones, and around 50 thousand units of Apollo America's Combination Smoke and Carbon Monoxide or CO Detectors.
RTTNews | 1 day ago
TSX Pares Some Gains After Hitting Fresh Record High

TSX Pares Some Gains After Hitting Fresh Record High

Canadian stocks are up in positive territory in late morning trade on Friday, amid slightly easing concerns about tariffs following somewhat encouraging phone calls between the U.S. President Donald Trump and Chinese Premier Xi. Investors are also digesting the nation's jobs data, as well the non-farm payrolls data from the U.S.
RTTNews | 1 day ago