Endo Int'l Reports Top-line Results From Phase 2 Study Of CCH For Adhesive Capsulitis Of Shoulder

RTTNews | 1153天前
Endo Int'l Reports Top-line Results From Phase 2 Study Of CCH For Adhesive Capsulitis Of Shoulder

(RTTNews) - Pharmaceutical company Endo International plc (ENDP) announced Friday top-line results from its Phase 2 study of Collagenase Clostridium Histolyticum (CCH) in participants with adhesive capsulitis (AC) of the shoulder, commonly known as "frozen shoulder."

The Phase 2 study participants receiving up to three doses of CCH showed some improvement in the change from baseline in the adapted American Shoulder and Elbow Surgeons (ASES) Standardized Shoulder Form composite score for the affected shoulder at the Day 95 visit.

The difference compared to those study participants receiving placebo was not statistically significant.

The safety profile of CCH in the Phase 2 study was consistent with the known safety profile from other studies.

The Phase 2 trial enrolled 198 participants with unilateral idiopathic AC of the shoulder with restricted range of motion (ROM) and function in the affected shoulder. Participants were randomized 1:1 to receive CCH or placebo administered by ultrasound-guided injection.

read more
Endo Intl's Par Pharma Recalls Treprostinil Injection For Silicone Particulates

Endo Intl's Par Pharma Recalls Treprostinil Injection For Silicone Particulates

Dublin, Ireland -based Endo International plc announced that its operating company Par Pharmaceutical, Inc. is recalling one lot of Treprostinil Injection 20mg/20mL (1mg/mL) to the consumer level. The recall, being conducted along with the U.S. Food and Drug Administration, is due to the potential for the presence of silicone particulates in the product solution.
RTTNews | 533天前
Endo International Says Health Canada Approves XCOPRI To Treat Epilepsy

Endo International Says Health Canada Approves XCOPRI To Treat Epilepsy

Specialty pharmaceutical company Endo International plc (ENDPQ.PK) announced Thursday that its operating company Paladin Labs, Inc. (PLB.TO) has received Health Canada's approval of XCOPRI (cenobamate tablets) for adjunctive therapy in the management of partial-onset seizures in adults with epilepsy who are not satisfactorily controlled with conventional therapy.
RTTNews | 790天前
European Shares Seen Higher At Open

European Shares Seen Higher At Open

European stocks are seen opening broadly higher on Thursday even as Nvidia's disappointing sales forecast raised concerns about the AI spending boom.
RTTNews | 18分钟前
Sensex Nifty Decline On Tariff Worries

Sensex Nifty Decline On Tariff Worries

Indian shares opened on a sluggish note on Thursday after U.S. President Donald Trump's 50 percent tariffs on Indian goods came into effect, impacting trade worth billions of dollars and risking Washington-New Delhi ties.
RTTNews | 1小时10分钟前
European Economic News Preview: Eurozone Economic Sentiment Data Due

European Economic News Preview: Eurozone Economic Sentiment Data Due

Economic confidence and monetary aggregates from the euro area and flash GDP from Switzerland are the top economic news due on Thursday. At 3.00 am ET, the State Secretariat for Economic Affairs is slated to release Swiss GDP data for the second quarter. The economy is expected to grow 0.1 percent sequentially after rising 0.5 percent in the first quarter.
RTTNews | 1小时11分钟前
Australian Market Trims Early Losses In Mid-market

Australian Market Trims Early Losses In Mid-market

The Australian market is trimming early losses in mid-market moves on Thursday, giving up some of the gains in the previous session, despite the broadly positive cues from Wall Street overnight. The benchmark S&P/ASX 200 is falling to near the 8,950 level, with weakness in iron ore miners, energy and technology stocks partially offset by gains in financial stocks.
RTTNews | 2小时37分钟前
Asian Markets Trade Mostly Higher

Asian Markets Trade Mostly Higher

Asian stock markets are mostly higher on Thursday, following the broadly positive cues from Wall Street overnight, as traders remain optimistic the US Fed will cut interest rates at their next meeting in September. They also remain cautious ahead of the release of key US economic data later in the week, including second quarter GDP and the Fed's preferred readings on consumer price inflation.
RTTNews | 2小时52分钟前