NRx Pharma Achieves Data-lock In Phase 2b/3 Suicidal Treatment Resistant Bipolar Depression Study

RTTNews | 451 days ago
NRx Pharma Achieves Data-lock In Phase 2b/3 Suicidal Treatment Resistant Bipolar Depression Study

(RTTNews) - Biopharmaceutical company NRx Pharmaceuticals, Inc. (NRXP) announced Monday that it has achieved data-lock in its Phase 2b/3 Suicidal Treatment Resistant Bipolar Depression Study with NRX-101. With data-lock, the complete data set is transferred for independent statistical analysis. The top-line data release is expected in April 2024.

With positive data from this study and FDA comment, NRx becomes eligible to receive the balance of its first milestone (an additional $4 million) from partners Alvogen, Inc. and Lotus Pharmaceuticals, Inc. (1745.TW).

These partners would then be responsible for all future development costs in this indication. NRx retains rights for all other indications, including chronic pain and PTSD. NRx is then poised to receive $320 million in further milestones along with mid-teen royalties on Net Sales.

NRX-101 has been awarded Breakthrough Therapy Designation, Fast Track Designation, a Biomarker Letter of Support, and a Special Protocol Agreement by the FDA for treatment of Suicidal Treatment Resistant Bipolar Depression.

The Phase 2b/3 trial is a randomized, prospective, multicenter, double-blind study comparing NRX-101 to lurasidone over six weeks.

read more
Australian Market Trims Early Gains In Mid-market

Australian Market Trims Early Gains In Mid-market

The Australian stock market is trimming its early gains in mid-market moves on Friday, reversing the slight losses in the previous session, following the broadly positive cues from Wall Street overnight. The benchmark S&P/ASX 200 is moving above the 8,600 level, with gains in financial and technology stocks partially offset by weakness in mining stocks.
RTTNews | 55 minutes ago
Asian Markets Mixed In Cautious Trades

Asian Markets Mixed In Cautious Trades

Asian stock markets are trading mixed on Friday, following the broadly positive cues from Wall Street overnight, as traders continue to be cautious amid ongoing uncertainty over trade deals between the U.S. and its trade partner countries as well as the threat of heavy tariffs. Meanwhile, the stronger-than-expected U.S. jobs report helped ease investor concerns about a potential economic slowdown.
RTTNews | 1h 1min ago
Sensex, Nifty Seen Slightly Higher At Open

Sensex, Nifty Seen Slightly Higher At Open

Indian shares look set to open on a positive note Friday as a stronger-than-expected U.S. jobs report helped ease investor concerns about a potential economic slowdown.
RTTNews | 1h 47min ago
Higher Open Called For Thai Stock Market

Higher Open Called For Thai Stock Market

The Thai stock market has moved higher in four straight sessions, collecting almost 50 points or 4.6 percent along the way. The Stock Exchange of Thailand now sits just above the 1,125-point plateau and it's expected to see further upside on Friday.
RTTNews | 2h 18min ago
Japanese Market Modestly Higher

Japanese Market Modestly Higher

Extending the slight gains in the previous session, the Japanese market is modestly higher on Friday, following the broadly positive cues from Wall Street overnight. The Nikkei 225 is moving well above the 39,850 level, with gains in exporters, financial and technology stocks.
RTTNews | 2h 36min ago
Indonesia Bourse Expected To Halt Losing Streak

Indonesia Bourse Expected To Halt Losing Streak

The Indonesia stock market has finished lower in three straight sessions, slumping almost 50 points or 0.8 percent along the way. The Jakarta Composite Index now sits just shy of the 6,880-point plateau although it may stop the bleeding on Friday.
RTTNews | 2h 48min ago